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1

Translocation of proteins across membranes

Ilari Suominen, Pekka Mäntsälä

Journal:

International Journal of Biochemistry

Année:

1983

Langue:

english

Fichier:

PDF, 1.39 MB

english, 1983

2

Hybrid Anthracyclines from a Genetically Engineered Streptomyces g alilaeus Mutant

Kunnari, Tero J., Ylihonko, Kristiina P. J., Klika, Karel D., Mäntsälä, Pekka I., Hakala, Juha M. L.

Journal:

Journal of Organic Chemistry

Année:

2000

Langue:

english

Fichier:

PDF, 121 KB

english, 2000

3

Stable-light-emitting Escherichia coli as a biosensor

Matti Korpela, Pekka Mäntsälä, Esa-Matti Lilius, Matti Karp

Journal:

Année:

1989

Langue:

english

Fichier:

PDF, 307 KB

english, 1989

4

Artificial Reconstruction of Two Cryptic Angucycline Antibiotic Biosynthetic Pathways

Kaisa Palmu, Keishi Ishida, Pekka Mäntsälä, Christian Hertweck, Mikko Metsä-Ketelä

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 268 KB

english, 2007

5

Identification of Late-Stage Glycosylation Steps in the Biosynthetic Pathway of the Anthracycline Nogalamycin

Vilja Siitonen, Magnus Claesson, Pekka Patrikainen, Maria Aromaa, Prof. emer. Pekka Mäntsälä, Prof. Gunter Schneider, Dr. Mikko Metsä-Ketelä

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 634 KB

english, 2012

6

Sequential Action of Two Flavoenzymes, PgaE and PgaM, in Angucycline Biosynthesis: Chemoenzymatic Synthesis of Gaudimycin C

Pauli Kallio, Zhanliang Liu, Pekka Mäntsälä, Jarmo Niemi, Mikko Metsä-Ketelä

Journal:

Chemistry & Biology

Année:

2008

Langue:

english

Fichier:

PDF, 418 KB

english, 2008

7

Characterization of the Alnumycin Gene Cluster Reveals Unusual Gene Products for Pyran Ring Formation and Dioxan Biosynthesis

Terhi Oja, Kaisa Palmu, Hanna Lehmussola, Outi Leppäranta, Kati Hännikäinen, Jarmo Niemi, Pekka Mäntsälä, Mikko Metsä-Ketelä

Journal:

Chemistry & Biology

Année:

2008

Langue:

english

Fichier:

PDF, 438 KB

english, 2008

8

Hybrid anthracyclines by a genetically engineered Streptomyces galilaeus mutant

Tero Kunnari, Jarmo Niemi, Kristiina Ylihonko, Pekka Mäntsälä, Juha Hakala

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1997

Langue:

english

Fichier:

PDF, 114 KB

english, 1997

9

Incorrectly folded aromatic polyketides from polyketide reductase deficient mutants

Tero Kunnari, Kristiina Ylihonko, Anne Hautala, Karel D. Klika, Pekka Mäntsälä, Juha Hakala

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1999

Langue:

english

Fichier:

PDF, 195 KB

english, 1999

10

Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline

Jaana Kantola, Gloria Blanco, Anne Hautala, Tero Kunnari, Juha Hakala, Carmen Mendez, Kristiina Ylihonko, Pekka Mäntsälä, Jose Salas

Journal:

Chemistry & Biology

Année:

1997

Langue:

english

Fichier:

PDF, 494 KB

english, 1997

11

Site-directed mutagenesis of putative active-site residues ofBacillus stearothermophilusα-amylase

Mauno Vihinen, Sari Helin, Pekka Mäntsälä

Journal:

Molecular Engineering

Année:

1991

Langue:

english

Fichier:

PDF, 2.12 MB

english, 1991

12

Expression of luciferase genes from different origins inBacillus subtilis

Jorma Lampinen, Leeni Koivisto, Matti Wahlsten, Pekka Mäntsälä, Matti Karp

Journal:

Molecular Genetics and Genomics

Année:

1992

Langue:

english

Fichier:

PDF, 595 KB

english, 1992

13

Secretion ofβ-lactamase byEscherichia coli in vivoandin vitro: effect of cerulenin

Pekka Mäntsälä, Hannu Lehtinen

Journal:

Antonie van Leeuwenhoek

Année:

1982

Langue:

english

Fichier:

PDF, 839 KB

english, 1982

14

Transfer of nitrogen fixation genes intoPseudomonas putidaisolated from Finnish tundra soil

Hannu Lehtinen, Pekka Mäntsälä

Journal:

Antonie van Leeuwenhoek

Année:

1981

Langue:

english

Fichier:

PDF, 443 KB

english, 1981

15

Oxidation of crocein orange G by lignin peroxidase isoenzymes

Pauli Ollikka, Tiina Harjunpää, Kaisa Palmu, Pekka Mäntsälä, Ilari Suominen

Journal:

Applied Biochemistry and Biotechnology

Année:

1998

Langue:

english

Fichier:

PDF, 697 KB

english, 1998

16

Mutational Analysis of theBacillus subtilis purAOperator Site

Pekka Rappu, Mari Leppihalme, Pekka Mäntsälä

Journal:

Current Microbiology

Année:

2005

Langue:

english

Fichier:

PDF, 115 KB

english, 2005

17

Coproduction of several exoenzymes in Bacillus subtilis

Maija Sippola, Pekka Mäntsälä

Journal:

FEMS Microbiology Letters

Année:

1981

Langue:

english

Fichier:

PDF, 344 KB

english, 1981

18

Comparison of levansucrase from Bacillus subtilis and from Bacillus amyloliquefaciens

Pekka Mäntsälä, Mailis Puntala

Journal:

FEMS Microbiology Letters

Année:

1982

Langue:

english

Fichier:

PDF, 281 KB

english, 1982

19

Suppression of growth defects of α-amylase secreting Escherichia coli by signal sequence fusion

Ilari Suominen, Jarmo Käpylä, Carola Tilgmann, Virpi Glumoff, Pekka Mäntsälä

Journal:

FEMS Microbiology Letters

Année:

1988

Langue:

english

Fichier:

PDF, 359 KB

english, 1988

20

An efficient approach for screening minimal PKS genes from Streptomyces

Mikko Metsä-Ketelä, Virpi Salo, Laura Halo, Anne Hautala, Juha Hakala, Pekka Mäntsälä, Kristiina Ylihonko

Journal:

FEMS Microbiology Letters

Année:

1999

Langue:

english

Fichier:

PDF, 227 KB

english, 1999

21

Modification of aklavinone and aclacinomycins in vitro and in vivo by rhodomycin biosynthesis gene products

Yulong Wang, Jarmo Niemi, Pekka Mäntsälä

Journal:

FEMS Microbiology Letters

Année:

2002

Langue:

english

Fichier:

PDF, 222 KB

english, 2002

22

Structure of the polyketide cyclase SnoaL reveals a novel mechanism for enzymatic aldol condensation

Sultana, Azmiri, Kallio, Pauli, Jansson, Anna, Wang, Ji-Shu, Niemi, Jarmo, Mäntsälä, Pekka, Schneider, Gunter

Journal:

The EMBO Journal

Année:

2004

Langue:

english

Fichier:

PDF, 448 KB

english, 2004

23

Comparison of d-malate and β,β-dimethylmalate dehydrogenases from Pseudomonas fluorescens UK-1

Matti Lähdesmäki, Pekka Mäntsälä

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Année:

1980

Langue:

english

Fichier:

PDF, 537 KB

english, 1980

24

Evidence for the importance of cysteine and arginine residues in Pseudomonas fluorescens UK-1 pantoate dehydrogenase

Tuula Myöhänen, Pekka Mäntsälä

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Année:

1980

Langue:

english

Fichier:

PDF, 522 KB

english, 1980

25

Tailoring Enzymes Involved in the Biosynthesis of Angucyclines Contain Latent Context-Dependent Catalytic Activities

Pekka Patrikainen, Pauli Kallio, Keqiang Fan, Karel D. Klika, Khaled A. Shaaban, Pekka Mäntsälä, Jürgen Rohr, Keqian Yang, Jarmo Niemi, Mikko Metsä-Ketelä

Journal:

Chemistry & Biology

Année:

2012

Langue:

english

Fichier:

PDF, 734 KB

english, 2012

26

Discovery of a Two-Component Monooxygenase SnoaW/SnoaL2 Involved in Nogalamycin Biosynthesis

Vilja Siitonen, Bastian Blauenburg, Pauli Kallio, Pekka Mäntsälä, Mikko Metsä-Ketelä

Journal:

Chemistry & Biology

Année:

2012

Langue:

english

Fichier:

PDF, 638 KB

english, 2012

27

Cloning, sequencing, expression and characterization of three anti-estradiol-17β Fab fragments

Maria Pajunen, Petri Saviranta, Piitu Jauria, Matti Karp, Kim Pettersson, Pekka Mäntsälä, Timo Lövgren

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Année:

1997

Langue:

english

Fichier:

PDF, 423 KB

english, 1997

28

Modifications of aclacinomycin T by aclacinomycin methyl esterase (RdmC) and aclacinomycin-10-hydroxylase (RdmB) from Streptomyces purpurascens

Yulong Wang, Jarmo Niemi, Kalervo Airas, Kristiina Ylihonko, Juha Hakala, Pekka Mäntsälä

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Année:

2000

Langue:

english

Fichier:

PDF, 447 KB

english, 2000

29

Purification of pantoate and dimethylmalate dehydrogenase from Pseudomonas fluorescens UK-1

Pekka Mäntsälä

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Année:

1978

Langue:

english

Fichier:

PDF, 506 KB

english, 1978

30

Conserved residues of liquefying α-amylases are concentrated in the vicinity of active site

Mauno Vihinen, Pekka Mäntsälä

Journal:

Biochemical and Biophysical Research Communications

Année:

1990

Langue:

english

Fichier:

PDF, 3.99 MB

english, 1990

31

1-Anilino-8-naphthalene sulfonate and N-phenyl-1-naphthylamine as the indicators of bacterial thermosensitivity

Pekka Mäntsälä, Matti Lang

Journal:

Année:

1973

Langue:

english

Fichier:

PDF, 220 KB

english, 1973

32

The potential of VCD to resolve the epimer vs. inverse epimer quandary

Karel D. Klika, Petri Tähtinen, Pekka Mäntsälä, Jarmo Niemi, Mikko Metsä-Ketelä

Journal:

Computational and Theoretical Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 902 KB

english, 2012

33

Crystal Structure of Aclacinomycin-10-Hydroxylase, a S-Adenosyl-l-Methionine-dependent Methyltransferase Homolog Involved in Anthracycline Biosynthesis in Streptomyces purpurascens

Anna Jansson, Jarmo Niemi, Ylva Lindqvist, Pekka Mäntsälä, Gunter Schneider

Journal:

Journal of Molecular Biology

Année:

2003

Langue:

english

Fichier:

PDF, 2.90 MB

english, 2003

34

Crystal Structure of the Polyketide Cyclase AknH with Bound Substrate and Product Analogue: Implications for Catalytic Mechanism and Product Stereoselectivity

Pauli Kallio, Azmiri Sultana, Jarmo Niemi, Pekka Mäntsälä, Gunter Schneider

Journal:

Journal of Molecular Biology

Année:

2006

Langue:

english

Fichier:

PDF, 726 KB

english, 2006

35

Crystal Structures of SnoaL2 and AclR: Two Putative Hydroxylases in the Biosynthesis of Aromatic Polyketide Antibiotics

Philipp Beinker, Bernhard Lohkamp, Taina Peltonen, Jarmo Niemi, Pekka Mäntsälä, Gunter Schneider

Journal:

Journal of Molecular Biology

Année:

2006

Langue:

english

Fichier:

PDF, 936 KB

english, 2006

36

Crystal Structures of Two Aromatic Hydroxylases Involved in the Early Tailoring Steps of Angucycline Biosynthesis

Hanna Koskiniemi, Mikko Metsä-Ketelä, Doreen Dobritzsch, Pauli Kallio, Hanna Korhonen, Pekka Mäntsälä, Gunter Schneider, Jarmo Niemi

Journal:

Journal of Molecular Biology

Année:

2007

Langue:

english

Fichier:

PDF, 2.45 MB

english, 2007

37

A Nested Gene in Streptomyces Bacteria Encodes a Protein Involved in Quaternary Complex Formation

Pauli Kallio, Zhanliang Liu, Pekka Mäntsälä, Jarmo Niemi, Mikko Metsä-Ketelä

Journal:

Journal of Molecular Biology

Année:

2008

Langue:

english

Fichier:

PDF, 774 KB

english, 2008

38

Structural Basis for Substrate Recognition and Specificity in Aklavinone-11-Hydroxylase from Rhodomycin Biosynthesis

Ylva Lindqvist, Hanna Koskiniemi, Anna Jansson, Tatyana Sandalova, Robert Schnell, Zhanliang Liu, Pekka Mäntsälä, Jarmo Niemi, Gunter Schneider

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 818 KB

english, 2009

39

Alnumycins A2 and A3: new inverse-epimeric pairs stereoisomeric to alnumycin A1

Terhi Oja, Petri Tähtinen, Nadine Dreiack, Pekka Mäntsälä, Jarmo Niemi, Mikko Metsä-Ketelä, Karel D. Klika

Journal:

Tetrahedron: Asymmetry

Année:

2012

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2012

40

Modification of aklavinone and aclacinomycins in vitro and in vivo by rhodomycin biosynthesis gene products

Yulong Wang, Jarmo Niemi, Pekka Mäntsälä

Journal:

FEMS Microbiology Letters

Année:

2002

Langue:

english

Fichier:

PDF, 224 KB

english, 2002

41

An efficient approach for screening minimal PKS genes from Streptomyces

Mikko Metsä-Ketelä, Virpi Salo, Laura Halo, Anne Hautala, Juha Hakala, Pekka Mäntsälä, Kristiina Ylihonko

Journal:

FEMS Microbiology Letters

Année:

1999

Langue:

english

Fichier:

PDF, 230 KB

english, 1999

42

Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster

Kaj Räty, Jaana Kantola, Anne Hautala, Juha Hakala, Kristiina Ylihonko, Pekka Mäntsälä

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 146 KB

english, 2002

43

C-terminal truncations of a thermostable Bacillus stearothermophilus α-amylase

Vihinen, Mauno, Peltonen, Taina, Iitiä, Antti, Suominen, Ilari, Mäntsälä, Pekka

Journal:

Protein Engineering Design and Selection

Année:

1994

Langue:

english

Fichier:

PDF, 6.05 MB

english, 1994

44

Expression in E. coli and purification of intracellular proteins by fusion to cyclomaltodextrin glucanotransferase

Jukka Hellman, Sari Paavilainen, Pekka Mäntsälä

Journal:

Journal of Biotechnology

Année:

1992

Langue:

english

Fichier:

PDF, 2.44 MB

english, 1992

45

Construction of an Escherichia coli export-affinity vector for expression and purification of foreign proteins by fusion to cyclomaltodextrin glucanotransferase

Jukka Hellman, Pekka Mäntsälä

Journal:

Journal of Biotechnology

Année:

1992

Langue:

english

Fichier:

PDF, 1.34 MB

english, 1992

46

Epimers vs. inverse epimers: the C-1 configuration in alnumycin A1

Tähtinen, Petri, Oja, Terhi, Dreiack, Nadine, Mäntsälä, Pekka, Niemi, Jarmo, Metsä-Ketelä, Mikko, Klika, Karel D.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 472 KB

english, 2012

47

Tracing the Evolution of Angucyclinone Monooxygenases: Structural Determinants for C-12b Hydroxylation and Substrate Inhibition in PgaE

Kallio, Pauli, Patrikainen, Pekka, Belogurov, Georgiy A., Mäntsälä, Pekka, Yang, Keqian, Niemi, Jarmo, Metsä-Ketelä, Mikko

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 4.31 MB

english, 2013

48

Structural and Functional Analysis of Angucycline C-6 Ketoreductase LanV Involved in Landomycin Biosynthesis

Paananen, Pasi, Patrikainen, Pekka, Kallio, Pauli, Mäntsälä, Pekka, Niemi, Jarmo, Niiranen, Laila, Metsä-Ketelä, Mikko

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1.82 MB

english, 2013

49

Extracellular production of cloned α-amylase by Escherichia coli

Suominen, Ilari, Karp, Matti, Lähde, Matti, Kopio, Anja, Glumoff, Tuomo, Meyer, Peter, Mäntsälä, Pekka

Journal:

Année:

1987

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1987

50

Characterization of lignin peroxidase-encoding genes from lignin-degrading basidiomycetes

Huoponen, Kirsi, Ollikka, Pauli, Kälin, Markus, Walther, Isabelle, Mäntsälä, Pekka, Reiser, Jakob

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 680 KB

english, 1990